Platelet activation and microfilament bundling.

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Platelet activation and microfilament bundling

Human platelets were obtained in the fully resting state by treating discoid populations with 1.5 mM tetracaine and in the activated state by treatment with 2 microM A-23187. After gel filtration or washing, respectively, platelet suspensions were lysed with 1% Triton X-100 at pH 6.8. The precipitates from resting platelets viewed by negative staining appeared predominantly granular with a few ...

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 1981

ISSN: 0021-9525,1540-8140

DOI: 10.1083/jcb.89.1.146